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Literature summary extracted from

  • Mac Sweeney, A.; Lange, R.; Fernandes, R.P.; Schulz, H.; Dale, G.E.; Douangamath, A.; Proteau, P.J.; Oefner, C.
    The crystal structure of E. coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation (2005), J. Mol. Biol., 345, 115-127.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.267 selenomethionine labelled enzyme in ternary complex with the antimalarial compound fosmidomycin and NADPH Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.267 fosmidomycin model for tight-binding mode of inhibition Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.267 Escherichia coli P45568
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